Projects under Negotiation

12 transnational research consortia are under negotiation to be funded under the umbrella of the NEURON JTC 2017 ‘Synaptic Dysfunction’. In total, 59 research groups from 15 European countries, Canada and Israel collaborate in these projects. The total funding volume of the call amounts to about 12.4 M€.

Projects and partners are shown below. Please click on “summary” to download a brief project overview

Acronym

Title

Coordinator (in bold) and Partners

ADIKHUMICE

VGLUT3 rare mutant and vulnerability to addiction

summary (pdf, 77 KB)

Salah El Mestikawy (CA)
Stephane Jamain (FR)
Florence Vorspan (FR)
Rafael Maldonado (ES)
Christian Rosenmund (DE)

iPS&Brain

A functional dissection of human nicotinic receptor polymorphisms linked to addiction and schizophrenia

summary (pdf, 75 KB)

Uwe Maskos (FR)
Huib Mansvelder (NL)
Petra Scholze (A)


KARTLE

Targeting aberrant KAinate Receptors in Temporal Lobe Epilepsy

summary (pdf, 78 KB)

Christophe Mulle (FR)
Valérie Crepel (FR)
Dirk Grimm (DE)
Bernard Pirotte (BE)

MAGNOLIA

Amygdala synaptic neuromodulatory mechanisms and role of mGlu4 in Autism Spectrum Disorders

summary (pdf, 79 KB)

Cyril GOUDET  (FR)
Ingrid EHRLICH                (DE)
Julie LE MERRER (FR)
Amadeu LLEBARIA (ES)

MicroSynDep

Microglial control of synaptic function in stress response and vulnerability to depression

summary (pdf, 78 KB)

Marie-Eve Tremblay (CA)
Igor Branchi (IT)
Martin Fuhrmann (DE)
Naguib Mechawar (CA)
Maciej Lalowski (FI)
Valeria Mondelli (UK)
Bozena Kaminska (PL)

MISST

Multi-scale investigation of synaptic dysfunction after stroke

summary (pdf, 79 KB)

Valentin U.Nägerl (FR)
Nikolaus Plesnila (DE)
Jérôme Badaut (FR)
Leszek Kaczmarek (PL)
Javier Defelipe (ES)
Baiba Jansone (LV)

NMDAR-PSY

Understanding psychosis, cognitive impairment and motor symptoms induced by NMDA receptor dysfunction: from mechanisms to prevention and therapy

summary (pdf, 95 KB)

Dragos Inta (DE)
Hannah Monyer (DE)
Stefan Borgwardt (CH)
Uriel Heresco-Levy (IL)
Ole Andreassen (NO)
Raul Muresan (RO)

SleepLess

Imaging synaptic plasticity in therapeutic sleep deprivation for major depression

summary (pdf, 75 KB)

David Elmenhorst (DE)
Jeroen Verhaeghe (BE)
Pedro Rosa-Neto (CA)

SNAREopathy

Mechanisms of neuropsychiatric genetic diseases of the SNARE complex: towards therapeutic intervention

summary (pdf, 77 KB)

Ruud Toonen (NL)
Federico Zara (IT)
Holger Lerche (DE)
Christian Freund (DE)
Camila Esguerra (NO)

SYNSCHIZ

Linking synaptic dysfunction to disease mechanisms in schizophrenia - a multilevel investigation

summary (pdf, 78 KB)

Ole Andreassen (NO)
Marcella Rietschel (DE)
Stefan Borgwardt (CH)
Marja-Leena Linne (FI)
Dirk Schubert (NL)
Magdalena Budisteanu (RO)

topdownPTSD

Mapping and interrogating top-down control of the memory engram of the posttraumatic stress disorder

summary (pdf, 76 KB)

Mazahir Hasan (ES)
Stefano Puglisi-Allegra (IT)
Agnès Gruart i Massó, (ES)
Philipp Böhm-Sturm (DE)
Stephanie Le Hellard (NO)
Ewa Oglodek (PL)

TREAT-SNGAP

Synaptic Dysfunction in Intellectual Disability Caused by SYNGAP1. Translational Research to Develop Human Models and Advance Pharmacological Treatments.

summary (pdf, 95 KB)

Àlex Bayés (ES)
Oliver Brüstle (DE)
Daniel Choquet (FR)
Jacques Michaud (CA)
Barbara Treutlein (DE)

 


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